Quercetin is a type of flavonoid present in many fruits, vegetables, and grains. Therefore, It is one of the most abundant antioxidants in our diet. It also plays an important role in helping your body combat free radical damage, which is linked to chronic diseases. In addition, its antioxidant properties may help reduce inflammation, allergy symptoms, and blood pressure. Some doctors are advocating its use against SARS-CoV-2 (COVID-19), in combination with vitamin C, noting that Quercetin and Vitamin C have synergistic effects.

We have listed the best quercetin supplements available online below.

1. Now Foods Quercetin with Bromelain (Now Quercetin with Bromelain Amazon)

        $30 – $35

Each pill contains 400 mg of quercetin and 82.5 mg of bromelain. Take notice that 2 capsules twice daily (1,600mg total) is the recommended dosage.

The daily value (DV) for quercetin has not been determined.

Bromelain is found in Now Foods Quercetin supplements, which may help with absorption.

The FLCCC advises a daily dose of 250 mg for COVID-19 prophylaxis, while the Zelenko regimen suggests a daily dose of 500 mg. If you want to stay within the FLCCC – Zelenko protocol’s dose range, that would be 250 mg to 500 mg per day, or 1 Now Foods Quercetin pill per day.

A two-pack of top notch bromelain-enhanced quercetin from a giant in the health supplement industry. Reliable quality from a trustworthy brand. However, this may not be suitable for those with pineapple allergies due to the bromelain content.

Amazon Best Sellers: #3 Best Seller in Flavonoid Supplements
Rating: 4.7/ 5 – more than 5,000 customer reviews.
Our Take: If you are looking for the best value and are taking it on a long-term basis, this would be your choice.

2. Thorne Research Quercenase


Quercenase is a combination of quercetin phytosome and bromelain.
Quercetin phytosome is a new food-grade lecithin-based formulation of quercetin. It was created to overcome quercetin’s low bioavailability. Meanwhile, phytosome complexes are created by a patented process that binds a botanical extract to a phospholipid (phosphatidylcholine), which are key components of every cell membrane.
Each capsule contains 250 mg of quercetin phytosome and 100 mg of bromelain. Cost per capsule: $0.77.

Randomised Controlled Trial of 152 outpatients with COVID-19 in Pakistan. 76 patients that were treated with quercetin phytosom, showed lower mortality, ICU admission, and hospitalization.

(International Journal of General Medicine, May 2021)

A potent, science-backed formulation by a brand known for quality that is made with the purest ingredients for maximum efficacy. However, it is relatively pricier than many similar products on the market.

Amazon Best Sellers: #11 Best Seller in Flavonoid Vitamin Supplements.

Ratings: 4.7/5 – more than 390 customer reviews.

Amazon Review
I have histamine intolerance and had spent many years taking prescription and OTC drugs. I wanted to get away from drugs and my functional medicine doctor recommended d-hist.
It worked on my allergies but I would get migraines if I took it too often. I think it was the nettles. Anyway, I also didn’t like that they used magnesium stearate. I bought this and it works just as well as my Claritin did. I get relief from runny nose and sneezing as well as itchy skin. I will sometimes add some extra bromelain but I am very happy.
Thorne products are often more expensive but they use better ingredients and omit questionable ingredients that make production cheaper.
Our Take: If you are looking to buy from a reputable brand, this would be your choice.

3. MoxyVites Quercetin 500mg with Bromelain Supplement, Bioactive Phytosome Complex


Moxyvites quercetin complex is a combination of quercetin phytosome and bromelain. In order to improve the absorption and bioavailability by 20X, moxyvites’ technology binds quercetin with a glucose bond & incorporation of phospholipids into standardized extracts.


Their complex delivery system utilizes phytosome technology in which phytoconstituents react with phospholipids for better and improved bioavailability. Another benefit of this product is that it contains curcumin, which is well known for its anti-inflammatory and anti-oxidant effects.

Each capsule contains 250 mg of quercetin phytosome and 80 mg of bromelain. Cost per capsule: $0.29.
Amazon Best Sellers:

#31 Best Seller in Flavonoid Vitamin Supplements. 4.8 out of 5 overall ratings.

Our Take: If you are looking for the best value in terms of quercetin phytosome with bromelain and are taking it on a long-term basis, this would be your choice. 

4. Sandhu's Zinc Quercetin (Best Quercetin with Zinc)

A combination of 400 mg of quercetin and 11 mg of zinc to support immune health. Cost per capsule: $0.16.
For prevention of COVID-19, the FLCCC recommends 250 mg daily of quercetin and 30 mg of elemental zinc for prevention. Meanwhile, the Zelenko protocol recommends 500 mg daily of quercetin and 25 mg of elemental zinc for prevention. If you wish to stick to a dosage  within the range of the FLCCC – Zelenko protocols, 250 mg to 500 mg daily for quercetin and 25 to 30 mg for zinc would be recommended. 
One capsule of Sandhus quercetin and zinc will meet the prevention protocol requirement dosage for quercetin on a daily basis but the dosage for zinc is on the lower side. Therefore, you might wish to supplement your zinc with foods that are rich in zinc.
Amazon Best Sellers:
#3 Best Seller in Zinc Supplements.
Ratings: 4.8/5 – more than 7,000 customer reviews.

5. Natural Factors Bioactive Quercetin

Natural Factors Bioactive Quercetin EMIQ claims to have 40 times better absorption than ordinary quercetin. This is because they  use “EMIQ”, a proprietary formula made from “Enzymatically Modified IsoQuercetin”.

Dosage of quercetin is somewhat low (as compared to other brands) in each capsule. However, Natural Factors claims the quercetin is more bioavailable, which means your body gets a strong dose regardless.


Each capsule contains 167 mg of EMIQ and 50 mg of vitamin C. Natural Factors claims their formula will provide year-round protection while supporting a healthy inflammatory response and maintaining good sinus and upper respiratory function.



Amazon Best Sellers: #25 Best Seller in Flavonoid Vitamin Supplements. 4.8 out of 5 – more than 500 global ratings.
Our Take: Best Quercetin for Bioavailability
Amazon Review:
“This literally took away all of my excessive histamine responses within a couple of hours. the second day got even better. If you suffer from allergies or inflammation and would like a natural option, please consider this.” – Sparklebarbie
“I’ve been on quercetin for a long time for bad allergies – the kind that requires MULTIPLE antihistamines. (Mast Cell Activation Disorder – basically your body releases too much histamine to too many stimulus). This quercetin is WAY more potent and WAY more effective than regular quercetin. I take a lot less of this, and only once a day, and it really helps my allergies. It’s a little spendy but well worth it due to it’s effectiveness. Also this is a good brand that I trust. I’ve been researching and taking supplements for more than 20 years, and this one brand I always feel comfortable recommending to others.”

6. Mt Angel Vitamins Quercetin Zinc - Best Immune Support Supplement

Mt. Angel Vitamins quercetin zinc is a combination of quercetin, zinc, vitamin D3, C and bromelain. Quercetin works best when taken with vitamin C and Bromelain, as some evidence suggests they boost absorption.
For prevention of COVID-19, quercetin, zinc, vitamin D3 and vitamin C are part of the FLCCC I-MASK+ protocol and the Zelenko protocol.
Each Mt. Angel Quercetin Zinc capsule contains 265 mg of quercetin, 3.75 mg of zinc, 12.5 mcg of vitamin D3 and 60 mg of vitamin C. Cost per capsule: $0.20. (300 capsules per container).

Ratings: 4.7 out of 5 – more than 1,000 global ratings


Amazon Review:

My husband read the Swiss protocol for Covid 19 preventative and this has it all. So far so good no problems. No bad taste easy to swallow, our 12yr old son even has no problem.

Our Take: If you are looking for the best value in terms of quercetin, zinc, vitamin D3, vitamin C, and bromelain, all in one capsule; and are taking it on a long-term basis, this would be your choice. 

7. Amazing Formulas - Quercetin 500 Mg (Best for Vegetarians)

Amazon Best Sellers: #1 Best Seller in Flavonoid Vitamin Supplements. 4.7 out of 5 overall rating with more than 12,000 customer reviews.
Each Amazing Formulas Quercetin capsule contains 500 mg of quercetin dihydrate. Cost per capsule: $0.17. (120 vegetarian capsules per container).
Ratings: 4.7 out of 5 – More than 15,000 global ratings.
I’ve been sick twice in the past two months, one a mild cold, the other quite severe, DID NOT GET TESTED so can not attest to Covid 19. Anyway, once I got sick, I took 1000mg of Quercetin, combined with 200mg of Zinc Picolinate – ANECDOTAL EVIDENCE: I was free and clear of symptoms in the range of 6 to 10 hours, save for a lingering itch in my sinuses, which was gone after a good night sleep. Symptoms did not return in either case. This was ONE DOSE.
Our Take: If you are looking for best value in terms of quercetin suitable for vegetarians and vegans; and are taking it on a long term basis, this would be your choice.

8. Whole Food Quercetin Plus

– Organic Whole Foods

– Quercetin with Bromelain-Zinc-Vitamin C-Ginger-Bioflavonoids
– Immune, Cardiovascular & Respiratory System Support
– Natural Antioxidant
– Vegan, Non-GMO
– 180 Caps, 90 servings

– Immunity supporting properties, improves healthy seasonal immune system function, and reduces inflammation. 
– May improve health by aiding exercise performance, improving digestion, helping respiratory health, give your immune system the boost it needs, and enhance cognitive function.
– Manufactured in the USA. Made in a GMP-certified facility in the USA. Third-party tested. 



Quercetin 500 mg + 175 mg of Organic Whole Food Quercetin Blend (4 Organic Whole Food Quercetin source ingredients) 

+ 15 mg of Zinc Picolinate + 200 mg of Bromelain from Pineapple + 100 mg of Organic Ginger Root 

+ 125 mg of Vitamin C from Organic Acerola Cherries + 100 mg of Citrus Bioflavonoids from Organic Orange & Organic Lemon

– FREE from GMO, Alcohol, Preservatives, Soy Lecithin, Gelatin, Dairy, Sugar, Gluten, Shellfish, Nuts, Wheat, Stearates, Silicon Dioxide, fillers, Artificial Ingredients.



I am able to do much more before having to take a break. Also I have notice a very marked drop in BG an hour after taking. Definitely recommend.

9. Doctor's Best Quercetin Bromelain


– Non-GMO, Vegan, Gluten Free, Soy Free
– 180 Veggie Caps
– Bromelain 3000 GDU per capsule, has 500 Mg of Quercetin with 250 Mg Bromelain for a Serving size of 2 Capsules
– Quercetin and Bromelain enhances each other’s antioxidant and anti-inflammatory potential. This is because Quercetin is a bioflavonoid that has potent antioxidants while bromelain works as protein-digesting enzyme. Bromelain helps increase your body’s absorption and use of Quercetin.
– Helps support immune health, heart health, joint comfort, healthy digestions, respiratory health and inflammatory response.
– Quercetin helps ensure appropriate immune response, inhibits formation of free radicals and promotes circulatory health in part by supporting the integrity of small blood vessels.

i have sleep apnea and have TO sit up in a recliner to sleep because i can not use a CPAP. QUERCETIN CLEARS MY SINUS SO BOTH NOSTRILS ARE OPENED WITH OUT ANY NEGATIVE PHARMCEUUTICAL DRUG SIDE EFFECTS . i now sleep lying flat. thank you drs best. you formula.

Ratings: 4.7 out of 5 – 2,096 global ratings

10. BlueBonnet Super Quercetin

$36 – $40 > (currently unavailable on Amazon)

A potent blend of antioxidants and natural ingredients to ease allergies and boost immune response. Non-GMO and free of common allergens.
Amazon Best Sellers: #21 Best Seller in Flavonoid Vitamin Supplements. 4.8 out of 5 overall rating with more than 190 customer reviews.
Out Take: If you are looking for a potent antioxidant blend, this would be suitable for you.

Benefits of Quercetin Supplements

What does science have to say about quercetin? Can quercetin fight inflammation and reduce the risk of disease? Let’s dive into the science behind quercetin.

a. Antioxidative Properties

Bioflavonoids like quercetin provide benefits by working as antioxidants. 

b. Reduces Inflammation

In multiple studies, Quercetin has been shown to reduce inflammation. In this 8 week study involving 50 women with rheumatoid arthritis, participants took 500mg of quercetin per day or a placebo. The quercetin group reported less early morning stiffness, morning pain, and after-activity pain. 

Early studies on quercetin and inflammation are promising, although more large-scale human studies need to be performed to verify these benefits.

c. Reduces Allergy Symptoms

There’s evidence that quercetin reduces allergy symptoms. Researchers believe quercetin’s anti-inflammatory effects may relieve allergy symptoms.

A study published in Molecules in 2016, for example, found that quercetin could be effective for treating the anaphylactic (allergic) reaction in someone with peanut allergies. This similar study from 2006 concluded that quercetin was a “safe, natural therapy that may be used as primary therapy or in conjunction with conventional methods” for blocking allergies. 

It’s possible that quercetin has the same anti-allergy effect in humans, although more research needs to be done.

d. May Contribute in Fighting Cancer

Early research on the cancer-fighting benefits of quercetin is promising, although more research needs to be performed to verify these effects in humans.


In 2015, researchers reviewed available test tube and animal studies on quercetin and prostate cancer. After reviewing available evidence, researchers found that quercetin suppressed cell growth and induced cell death in prostate cancer cells.

This study published in 2017 in Oncology Reports took things a step further, finding that quercetin induced cancer cell death in nine types of cancer, including prostate cancer, colon cancer, and breast cancer.

Furthermore, in another 2017 study, researchers gave quercetin to mice with tumors. Researchers found that mice in the quercetin-treated group showed delayed tumor growth, no significant changes in daily behavior, significantly better survival ratings, and increased rates of cell death.

Bladder Cancer

In 2016, researchers published a landmark study in the American Journal of Cancer Research. Researchers analyzed quercetin’s effect on cancer cells in a test tube. They concluded, “We are the first to show that quercetin displays potent inhibition on bladder cancer cells via activation of AMPK pathway.”

e. Lowers Risk of Chronic Brain Disorders

Other evidence suggests quercetin lowers your risk of chronic brain disorders, including Alzheimer’s and dementia.

In this study published in Neuropharmacology in 2015, researchers gave quercetin to mice with Alzheimer’s. They injected them with quercetin every two days for three months. By the end of the study, the injections had reversed several markers of Alzheimer’s, and the mice performed much better on learning tests.

In a study published in 2018, researchers gave mice with Alzheimer’s a quercetin-rich diet. Researchers found the diet improved brain function in mice with early-middle stage Alzheimer’s, although it had no significant effect on middle-late stage Alzheimer’s.

Coffee and Alzheimer’s

You may have heard that coffee is linked to a reduced risk of Alzheimer’s. There’s certainly some research to back that claim up. However, recent research has suggested that quercetin (not caffeine) is the primary compound in coffee responsible for protective effects against Alzheimer’s.

f. Supports Cardiovascular Health

Some people use quercetin to reduce blood pressure and improve other measurements of cardiovascular health. High blood pressure raises your risk of heart disease, which is the leading cause of death in the United States. Approximately 1 in 3 American adults have high blood pressure.

Research suggests that quercetin reduces blood pressure levels. In this study published in 2002, researchers found that quercetin exhibited vasodilator effects, widening blood vessels and reducing blood pressure. 

Multiple human studies have suggested similar benefits. Researchers reviewed nine human studies involving 580 people. After reviewing available evidence, researchers found that taking more than 500 mg of quercetin supplement per day reduced systolic and diastolic blood pressure by 5.8mm Hg and 2.6 mm Hg, respectively. In other words, quercetin was shown to significantly improve blood pressure readings.

g. Anti-Aging

Some people take quercetin for its anti-aging effects. Antioxidants and anti-inflammatories – including quercetin – seem to have powerful anti-aging benefits. One study on young mice found that quercetin reduced mortality and extended lifespan. Another study from 2017 on human cells in test tubes found that quercetin reduced aging markers, with researchers concluding there was “anti-aging potential” for quercetin.

h. Improves Exercise Performance

Others take quercetin supplements to improve endurance and exercise performance. This 2011 study reviewed 11 quercetin studies involving 254 human subjects and found that quercetin provided a statistically significant benefit in human endurance exercise capacity (VO2 max) and endurance exercise performance, although the effect “is between trivial and small”.

i. Helps Control Blood Sugar

Finally, some diabetics take quercetin to help manage blood sugar. This study from 2019 found that taking 500mg of quercetin per day significantly reduced fasting plasma glucose (FPG) levels, suggesting that quercetin helped control fasting blood sugar. On another note,  this study in 2019 found similar results, finding that quercetin lowered serum glucose levels at doses of 10, 25, and 50mg per kg.

j. Coronavirus

Some suggest that quercetin could treat the COVID-19 coronavirus. Quercetin was shown to be effective against SARS, the Ebola virus, and the Zika virus. 

This 2019 study by researchers in Korea found that quercetin and other flavonoids may inhibit the proteolytic activity of SARS-CoV 3C-like protease, creating an antiviral effect.

Research on the coronavirus and quercetin is ongoing, and it’s unclear if quercetin will have similar antiviral effects against COVID-19. To be clear, there’s no evidence suggesting that quercetin treats, prevents, or manages the COVID-19 coronavirus, although research is ongoing.This


Most quercetin studies use a dosage of around 500 mg per day, although some studies use a dosage of 500mg taken twice per day.

Many supplements have a similar dosage, offering 500 mg to 1,200 mg of quercetin per serving.

For prevention of COVID-19, the FLCCC recommends 250 mg daily for prevention and the Zelenko protocol recommends 500 mg daily for prevention. If you wish to stick to the dosage which is within the range of the FLCCC – Zelenko protocols; that would be 250 mg to 500 mg daily. 

In some studies, researchers have given participants up to 5,000mg of quercetin per day with no reported side effects.



Quercetin has poor bioavailability. You might take a 1,200mg quercetin supplement, but your body only absorbs a small percentage of it. That’s why many quercetin supplements contain vitamin C or bromelain, as some evidence suggests they boost absorption.


There’s also some evidence that quercetin has a synergistic effect when combined with other flavonoid supplements. That’s why some quercetin supplements contain resveratrol, catechins, genistein, and other flavonoids.

Side Effects

in many cases, quercetin is generally recognized as safe. It’s found in many fruits and vegetables, and most people will experience no side effects when taking normal dosages of quercetin.

There have been few reported side effects for quercetin supplements. In some studies, large doses of quercetin (over 1,000mg) were linked with headaches, digestive issues, and tingling sensations. However, these symptoms were mild and uncommon.

Quercetin from food sources is safe for pregnant and breastfeeding women to take. However, there’s limited research on quercetin supplements in pregnant or breastfeeding women.

There’s no evidence that quercetin interacts with any drugs in a significant way. However, you should talk to your doctor before taking quercetin, especially if you are taking antibiotics or blood pressure medication.

Frequently Asked Questions About Quercetin

This section will help to answer some of the most commonly asked questions about Quercetin.
Capers, peppers (yellow and green), onions (red and white), shallots, asparagus, cherries, tomatoes, red apples, red grapes, broccoli, kale, red leaf lettuce, cranberries, blueberries, raspberries, green tea, black tea, and coffee are all excellent foods for quercetin.
The average person gets 10 to 100 mg of quercetin per day through normal dietary sources. This can vary greatly. Carefully track your diet over an extended period to figure out if you have a dietary deficiency of quercetin.
Early research in test tube and animal models shows that quercetin may have cancer-fighting properties. While these findings are promising, more large scale human studies need to be performed. Research is not definitive. Consult your physician before using any supplement to improve your cancer.
Researchers typically use a dose of 500 mg of quercetin per day in supplement form. Most quercetin supplements contain between 500 and 1200 mg of quercetin, although this can vary. Check out the nutritional label for your quercetin supplement to be sure.
Many people take quercetin supplements to avoid allergy symptoms. There’s evidence that quercetin has powerful anti-allergy benefits, although more research needs to be done.
Quercetin goes by a number of different names. You might see quercetin supplements labeled as bioflavonoid concentrate, bioflavonoid extract, or citrus bioflavonoid, for example.
Studies show that quercetin may reduce the onset of Alzheimer’s, particularly in the early and middle stages of the condition. However, studies have mostly been performed on mice and test tubes – not in humans.
Some studies show that quercetin boosts recovery after exercise. In some small studies, athletes taking quercetin after exercise had faster recovery than a control group. Researchers believe quercetin reduces oxidative stress and post-exercise inflammation, helping your body recover.
Most people experience no side effects from quercetin, and any side effects tend to be mild. Quercetin side effects include tingling and numbness, headache, and nausea. Your chance of experiencing side effects increases at higher dosages (over 1,000mg).
Bromelain is a naturally occurring, protein-digesting enzyme found in the stem of the pineapple. This nutrient boosts the absorption of quercetin by inhibiting inflammatory chemicals called prostaglandins. Bromelain may also decrease inflammation on its own.
Your body doesn’t absorb quercetin very effectively on its own. Some studies have shown that bromelain boosts the absorption of quercetin, which is why you find bromelain (or vitamin C) in many quercetin supplements.
Quercetin is found in two forms, rutin and glycosidic forms. The glucosides like isoquercitrin and isoquercetin, seem to be more bioavailable and quickly absorbed. This is compared to quercetin aglycone or quercetin glycosides, such as rutin (quercetin rutinoside).

In one study, researchers gave participants 2,000mg to 5,000mg of quercetin per day with no adverse effects or signs of toxicity reported. Generally, quercetin is safe to take even in high doses, although you may experience mild side effects like nausea, digestive issues, and headaches at high doses. Excessively high doses of quercetin could lead to kidney problems.

Experts recommend taking 400mg of quercetin twice a day between meals for hay fever. Also consult your doctor to help provide a more comprehensive and effective treatment for hay fever.

Most studies suggest that it’s safe to give quercetin to your child, although you should use only half the dose you’d use on an adult. Talk to your pediatrician before giving any quercetin to your child.
Studies have shown that quercetin stabilizes mast cells that release histamine. Histamine is the principal mediator of reactions to pollen and other allergies. This makes quercetin a natural antihistamine. Many people use quercetin to treat symptoms of hay fever, including runny nose, watering eyes, and itching.

You should start with a quercetin dosage of around 500mg per day to assess your tolerance. However, researchers have given participants up to 5,000mg of quercetin per day with few reported side effects. Look for symptoms like upset stomach and diarrhea. Excessively high doses of quercetin could lead to kidney problems.

Quercetin appears safe for anyone to take when used in normal dosages. However, there’s limited research on how quercetin supplements affect women who are pregnant or breastfeeding. People with high blood pressure, or anyone taking blood pressure medication, may also want to take to their doctor before taking a quercetin supplement.
If you’re allergic to pineapples, you should avoid quercetin supplements with bromelain. Bromelain, an enzyme in pineapples, is added to quercetin supplements to boost bioavailability. Overuse of bromelain can create problems for consumers.
Several studies have examined the effect of quercetin on aging. Quercetin is rich with anti-inflammatories and antioxidants, which could make it a powerful anti-aging compound. 

Quercetin liquid claims to be more bioavailable than other sources of quercetin. You take the liquid sublingually (underneath your tongue). However, limited research shows quercetin capsules or powders are more effective, and all forms of quercetin are absorbed poorly by the body.

Quercetin may help asthma by relaxing smooth muscles lining the airway, improving airway flow.

Most supplement companies use various plant or vegetable-based sources of quercetin. Check the label.

Some quercetin supplements are specifically marketed as citrus-free, making them ideal for those with citrus sensitivities. Read the label or official product website for your supplement to be sure that it is actually citrus-free.

There’s some evidence that quercetin helps with diabetes, helping your body manage blood sugar levels during fasting. However, more research needs to be done to verify these benefits.

Quercetin supplements are generally labeled non-GMO. Check the label to verify your quercetin supplement is not made from genetically modified ingredients. Content

Final Thoughts

In conclusion, Quercetin is a bioflavonoid with potent antioxidant and anti-inflammatory effects. Many take quercetin supplements daily to support various body systems.

Some people take quercetin supplements for allergies. Others take it to boost the immune system. Others take quercetin for general anti-aging or health and wellness.

Early research on quercetin is promising, and new human studies are released every year validating certain quercetin benefits.