Best Formula for Reflux and Constipation in USA 2022

Constipation and infant gastroesophageal reflux sometimes occur together and doubling the misery since both constipation and reflux may cause fussiness and digestive discomfort.


Constipation happen when bowel movements become less frequent and stools become difficult to pass. Furthermore, constipation can make your child more susceptible to reflux. When a baby’s intestines begin to back up and collect stool, the pressure in their abdominal cavity rises. This increased pressure on the stomach can push the contents of the stomach up into the esophagus, causing reflux.

Which Formulas Are Best for Reflux and Constipation?

A. Hydrolyzed Formula

Hydrolyzed formula is made by breaking down the proteins in cow’s milk formula into small pieces. Hydrolyzed proteins formula require less processing to absorb, it is good option for some newborns or infants who have difficulty digesting full-size proteins or have a history of digestive problems.


B. Amino-Acid Based Formula

This formula has been broken down so extensively that only amino acids remain.  Because amino acids are the building blocks of proteins, the baby receives all of the nutrients included in standard formula without having to break down the protein internally.


C. Goat Milk Formula

Because goat milk formula includes high quantities of prebiotic oligosaccharides, it may be good for babies with constipation. Prebiotic oligosaccharides may encourage the growth of beneficial intestinal bacteria, including lactobacilli. By encouraging the growth of these bacteria, your baby’s digestion may more efficient.

Best Formula for Reflux and Constipation 2022

1. Gerber Good Start SoothePro Formula (0-12 months)

Good Start Soothe formula features prebiotics, Comfort Proteins and probiotics that improve the good bacteria in tummies and promote soft stools; It’s our closest formula to breastmilk. Moreover, Gerber Good Start SoothePro Formula has expert-recommended DHA to support healthy brain and eye development.

Soothing Nutrition: Modeled after the complete nutrition and gentleness of breastmilk, this formula offers nutrition for babies up to 12 months experiencing colic, excessive crying, fussiness and gas. Comfort Proteins to help provide comfort for your little one’s tummy.

4.8 out of 5 – more than 1,290 global ratings
Gerber Good Start SoothePro Formula Reviews

2. Enfamil Enspire Gentlease Infant Formula (0-12 months)

Enfamil Gentlease Infant Formula provides a gentle start for sensitive tummies. It’s designed to have easy-to-digest proteins & eases fussiness, gas, and crying in just 24 hours*. Gentlease also has nutrients like choline and dha—brain-nourishing nutrition that’s important for your baby during the first 12 months. *compared to the same infants who had been fed routine infant formula at the beginning of the study.


– clinically shown to reduce fussiness, gas, and crying in 24 hours
– has an easy-to-digest protein blend for sensitive tummies
– #1 pediatrician recommended brand for gassy & fussy babies* *among pediatricians recommending a brand
– complete nutrition for healthy growth during your baby’s first year
– perfect for plan-ahead feedings

4.8 out of 5 – more than 600 global ratings
Enfamil Enspire Gentlease Infant Formula reviews:

3. Earth's Best Organic Gentle Infant Formula (0-12 months)

Earth's Best Organic Gentle & Easy To Digest Milk-Based Infant Formula with Iron, 21 oz. Can

Earth’s Best Organic Gentle Infant Formula with Iron is designed especially for babies with difficulty digesting proteins. It has partially hydrolyed whey and 25% the amount of lactose found in our standard, milk based formula to help reduce fussiness, gas and crying.


Made with organic dairy and fortified with iron, it also contains lutein for eyes and prebiotic fiber for immunity. All Earth’s Best Organic formula is produced from organic milk from cows fed certified organic grain and hay that are grown without synthetic pesticides or fertilizers.

4. Enfamil Nutramigen Infant Formula, Hypoallergenic and Lactose Free Formula with Enflora LGG

Best hypoallergenic formula for eczema
Delivers Clinically-Proven Relief when managing colic due to cow’s milk allergy for a happier, better-rested baby & mom

– FAST RELIEF NOW: As early as the first feeding, with 90% of infants improving within 48 hours

– INCLUDES LGG: The most extensively studied probiotic for allergy management and supporting the digestive health of your baby

– BRAIN SUPPORT: Nutramigen is a gentle, lactose free baby formula that has important nutrients found in breast milk such as Omega-3 DHA, ARA, and Choline that provide brain support

– IMMUNE SUPPORT: Helps support baby’s immune system to return to consuming traditional milk protein formula without an allergic response

4.8 out of 5 – more than 2,500 global ratings
Enfamil Nutramigen Infant Formula reviews:

5. Gerber Good Start Baby Formula Powder, Extensive HA, Hypoallergenic, Stage 1

Best hypoallergenic formula for CMPA
This hypoallergenic formula is designed for babies with cow’s milk protein allergies (CMPA). If your baby is suspected to have or is diagnosed with CMPA, your baby’s doctor might recommend changing from a routine formula to a hypoallergenic extensively hydrolyzed infant formula

For Cow’s Milk Protein Allergy: Cow’s milk protein allergy is the most common allergy among infants. This formula features 100 percent high-quality whey protein, broken down into tiny pieces and is designed to be well-tolerated

4.3 out of 5 – more than 500 global ratings
Gerber Good Start Extensive HA reviews:

6. Nestle Alfamino Amino Acid Based Infant Formula with Iron

Alfamino is a hypoallergenic amino acid based infant formula designed for infants with cow’s milk protein allergy, multiple food allergies or malabsorptive conditions. lfamino provides essential nutrients that infants need for growth and development and has a unique fat blend containing medium chain triglycerides (MCT) to facilitate fat absorption.

– Hypoallergenic Pediatric Formula

Use Under Medical Supervision: Alfamino Infant Formula is easy to digest and is lactose free and gluten free; For infants 0 to 12 months

Alfamino Amino Acid Based Infant Formula reviews on Amazon:

7. Neocate Amino Acid-Based Infant With DHA ARA

Neocate® Infant DHA/ARA is specially formulated for the dietary management of infants with cow milk allergy (CMA), multiple food allergies (MFA) and related conditions.

– Added nucleotides & DHA/ARA

– Dairy free

– Made in a dairy protein-free facility

– Soy oil free

– No artificial colors, flavors, sweeteners

– Kosher Pareve

– Halal


Neocate® Infant DHA/ARA is a specially formulated medical food and should only be used under medical supervision. It’s important to always contact a healthcare professional before making any changes to your baby’s diet.

8. Holle Goat Organic Milk Formula Stage 1 (From Birth)

Holle Goat Milk Formula Organic Infant Baby Milk Stage 1 USA Seller.

This European-made formula is suitable from birth and is ideal for supplementing with breast milk or exclusive bottle-feeding. 

– Contains DHA
– Gluten Free
– No added sugar
– EU Organic Regulated


The EU Organic logo guarantees strict adherence to EU organic regulations and the careful processing of raw materials used. Holle formula is made from 99% organically grown ingredients and the remaining 1% are vitamins and minerals, which are necessary for a baby’s development. After the 6th month, it is recommended advance to Holle goat Milk Formula Stage 2.

9. NANNY Care Stage 1 Infant Goat Milk Formula 900g (From Birth)

Another European-made formula, Nanny Care Goat Milk Infant Formula contains DHA (Omega 3 LCPs) as required by legislation for all infant formula. It is also easy to digest.


Moreover, this formula avoids palm oil (which can be constipating and is not as high quality nutritionally as milk fat) and has some actual goat’s cream in it which provides a superior blend of fats more similar to those in breast milk.

10. Kabrita Goat Milk Toddler Formula (1-2 Years)

Made with premium Dutch goat milk, Kabrita is easy to digest and is specially created for your 12-24 month (1 to 2-year-old) toddler. Our naturally A2 milk formula will help keep your little one comfortable while supplementing, weaning, or when changing formulas due to tummy troubles.


Kabrita is a great cow milk alternative for children who experience minor issues associated with cow milk consumption. Its mild, sweet taste makes it a popular choice, even among picky eaters. We also use an adapted whey-to-casein protein ratio for even better digestibility.

– No added preservatives, artificial colors and flavors

– Glyphosate pesticide-free certified

4.7 out of 5 – more than 950 global ratings
Kabrita Goat Milk Toddler Formula Review


A normal baby with mild acid reflux may spit up after feedings, but usually isn’t irritable. This problem usually stops after 12 months.

– Rest their stomach. Keep your baby from eating or drinking for 30 to 60 minutes after vomiting so that their stomach has time to recover.


– Give them fluids. after 3o minutes, start by giving your baby small amounts (0.5 oz or less) of fluid every 5 to 10 minutes. If your baby vomits the fluid out, wait another 30 minutes. Then start again with small amounts of fluid every 5 to 10 minutes. Use water, breast milk or a clear, noncarbonated liquid. 


– Medicines. If your child has a fever, ask your pediatrician for the appropriate medication.

– Avoid overfeeding. If the baby’s stomach is too full, some of the contents might be pushed back out. To reduce overfeeding, feed your baby smaller amounts more frequently.

– Burp your baby frequently. Extra gas in the stomach causes gas bubbles to escape, which has a tendency to bring the rest of the stomach’s contents up as well. Burp after and during meals.

– Limit active play after meals

– Hold your baby upright. Pressing on a baby’s belly right after feeding may push their stomach contents out. 

– Consider the formula. Frequent vomiting may serve as one of several signs that it’s time to consider alternative formulas with your pediatrician. 

– Give oatmeal. Only recommended for babies after 6 months old. Babies with reflux may need thicker food to order to swallow safely or reduce reflux. 

– Avoid tight diapers or clothing